Clopidogrel and Sertraline: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking clopidogrel with sertraline (an SSRI) increases your risk of bleeding. This happens because sertraline makes clopidogrel work stronger in your blood, which can cause unusual bruising or bleeding.

What to do: Tell your doctor that you take both medications. Do not stop either drug on your own. Your doctor may monitor you more closely or adjust your doses if needed.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clopidogrel — View full safety profile, side effects, and all known interactions.

Sertraline — View full safety profile, side effects, and all known interactions.

Other interactions with Clopidogrel

SEVEREwarfarinMODERATEomeprazoleMODERATEescitalopramMODERATEpantoprazoleMODERATEibuprofenMODERATEtrazodone

Other interactions with Sertraline

MODERATEvenlafaxineMODERATEwarfarinMODERATEtramadolMODERATElosartanMODERATElevothyroxineMODERATEatenolol

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.