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fluoxetine and naproxen — Drug Interaction

Can you take fluoxetine and naproxentogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking fluoxetine with naproxen increases your risk of bleeding. Naproxen is a pain reliever that can thin your blood when combined with fluoxetine, an antidepressant. This may cause unusual bruising, bleeding gums, or other bleeding problems.

What to do: Talk to your doctor or pharmacist about this combination. Do not stop taking either medication on your own. Your doctor may suggest a different pain reliever or monitor you more closely while taking both drugs together.

Source: FDA-approved drug labeling via openFDA

About These Medications

fluoxetine — View full safety profile, side effects, and all known interactions.

naproxen — View full safety profile, side effects, and all known interactions.

Other interactions with fluoxetine

MODERATEmetoprololMODERATElosartanMODERATEsertralineMODERATEbupropionMODERATEtramadolMODERATEibuprofen

Other interactions with naproxen

MODERATElisinoprilMODERATElosartanMODERATEhydrochlorothiazideMODERATEsertralineMODERATEfurosemideMILDgabapentin

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.