Tramadol and Venlafaxine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking tramadol with venlafaxine can change how your body processes tramadol. This may cause too much tramadol to build up in your blood, which could be unsafe. It might also reduce how well the medicine works or cause withdrawal symptoms.

What to do: Tell your doctor that you take both medicines. Do not stop taking either medication without talking to your doctor first. Your doctor may need to adjust your doses or watch you more carefully.

Source: FDA-approved drug labeling via openFDA

About These Medications

Tramadol — View full safety profile, side effects, and all known interactions.

Venlafaxine — View full safety profile, side effects, and all known interactions.

Other interactions with Tramadol

MODERATEtrazodoneMODERATEwarfarinMODERATEomeprazoleMODERATElosartanMODERATEgabapentinMODERATEamoxicillin

Other interactions with Venlafaxine

MODERATEwarfarinMODERATEmetoprololMODERATEescitalopramMODERATEsertralineMODERATEcitalopramMODERATEbupropion

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.