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bupropion and fluoxetine — Drug Interaction

Can you take bupropion and fluoxetinetogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking bupropion with fluoxetine can cause fluoxetine to build up in your body to unsafe levels. This may increase side effects like tremors, confusion, or irregular heartbeat.

What to do: Tell your doctor you're taking both medications. Your doctor may need to lower your fluoxetine dose. Keep taking both medicines as prescribed unless your doctor tells you to change.

Source: FDA-approved drug labeling via openFDA

About These Medications

bupropion — View full safety profile, side effects, and all known interactions.

fluoxetine — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.