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bupropion and tramadol — Drug Interaction

Can you take bupropion and tramadoltogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking bupropion with tramadol can cause tramadol to build up in your body to higher levels than normal. This could increase side effects like dizziness, drowsiness, nausea, or difficulty concentrating.

What to do: Talk to your doctor or pharmacist before taking these medicines together. They may need to adjust your doses or monitor you more closely. Do not stop either medication without speaking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

bupropion — View full safety profile, side effects, and all known interactions.

tramadol — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.