Doxycycline and Fluoxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Doxycycline and fluoxetine may interact and affect how your body processes these medications. This could change how well they work or increase side effects like dizziness, drowsiness, or coordination problems.

What to do: Talk to your doctor or pharmacist about taking these medicines together. Do not stop either medication without speaking to your doctor first. Tell them about any new symptoms you notice.

Source: FDA-approved drug labeling via openFDA

About These Medications

Doxycycline — View full safety profile, side effects, and all known interactions.

Fluoxetine — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.