Doxycycline and Tramadol: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking doxycycline with tramadol may cause tramadol to build up in your body to higher levels than normal. This could increase side effects like dizziness, drowsiness, or nausea.

What to do: Tell your doctor you're taking both medicines. Don't stop either medication on your own. Your doctor may adjust your doses or monitor you more closely to keep you safe.

Source: FDA-approved drug labeling via openFDA

About These Medications

Doxycycline — View full safety profile, side effects, and all known interactions.

Tramadol — View full safety profile, side effects, and all known interactions.

Other interactions with Doxycycline

MODERATEsimvastatinMODERATElosartanMODERATEwarfarinMODERATEpravastatinMODERATEfluoxetineMODERATEamoxicillin

Other interactions with Tramadol

MODERATEtrazodoneMODERATEwarfarinMODERATEvenlafaxineMODERATEomeprazoleMODERATElosartanMODERATEgabapentin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.