Duloxetine and Venlafaxine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking duloxetine and venlafaxine together can increase the amount of duloxetine in your body, making side effects more likely. Both drugs can also increase your risk of bleeding, especially if you take blood thinners or pain relievers like aspirin or ibuprofen.

What to do: Tell your doctor if you take both these medications. Do not stop taking them without talking to your doctor first. Your doctor may adjust your doses or monitor you more closely.

Source: FDA-approved drug labeling via openFDA

About These Medications

Duloxetine — View full safety profile, side effects, and all known interactions.

Venlafaxine — View full safety profile, side effects, and all known interactions.

Other interactions with Duloxetine

MODERATEomeprazoleMODERATEtramadolMODERATEmeloxicamMODERATEsertralineMODERATEibuprofenMODERATEfluoxetine

Other interactions with Venlafaxine

MODERATEwarfarinMODERATEmetoprololMODERATEescitalopramMODERATEsertralineMODERATEcitalopramMODERATEbupropion

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.