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hydrochlorothiazide and naproxen — Drug Interaction

Can you take hydrochlorothiazide and naproxentogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking naproxen with hydrochlorothiazide can harm your kidneys and reduce how well your blood pressure medicine works. Your kidneys may not filter waste properly, especially if you're older or already have kidney problems.

What to do: Talk to your doctor before taking naproxen. Your doctor may need to check your kidney function with blood tests while you take both medicines. Do not stop either medication without speaking to your doctor first.

Source: FDA-approved drug labeling via openFDA

About These Medications

hydrochlorothiazide — View full safety profile, side effects, and all known interactions.

naproxen — View full safety profile, side effects, and all known interactions.

Other interactions with hydrochlorothiazide

MODERATElisinoprilMODERATEmetforminMODERATElosartanMODERATEibuprofenMODERATEpropranololMODERATEaspirin

Other interactions with naproxen

MODERATElisinoprilMODERATElosartanMODERATEsertralineMODERATEfurosemideMODERATEescitalopramMILDgabapentin

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.