Duloxetine and Meloxicam: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking duloxetine (an antidepressant) with meloxicam (a pain reliever) together increases your risk of bleeding, especially in your stomach. This happens because both drugs affect how your blood clots.

What to do: Talk to your doctor or pharmacist before taking these medicines together. Do not stop either medication on your own. Your doctor may monitor you more closely or suggest a different pain reliever that is safer to use with duloxetine.

Source: FDA-approved drug labeling via openFDA

About These Medications

Duloxetine — View full safety profile, side effects, and all known interactions.

Meloxicam — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.