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duloxetine and omeprazole — Drug Interaction

Can you take duloxetine and omeprazoletogether? Here's what FDA data shows.

MODERATE

Interaction Found

Taking duloxetine and omeprazole together may cause duloxetine to build up in your body to higher levels. This could increase side effects like dizziness, nausea, or drowsiness. There is also a small increased risk of stomach bleeding, especially if you take NSAIDs or aspirin.

What to do: Talk to your doctor or pharmacist about taking these medications together. Do not stop taking either drug without talking to your doctor first. Tell them about all medications you take, including over-the-counter pain relievers.

Source: FDA-approved drug labeling via openFDA

About These Medications

duloxetine — View full safety profile, side effects, and all known interactions.

omeprazole — View full safety profile, side effects, and all known interactions.

Other interactions with duloxetine

SEVEREwarfarinMODERATEibuprofenMODERATEfluoxetineMODERATEnaproxenMODERATEaspirinMILDlorazepam

Other interactions with omeprazole

MODERATEoxycodoneMODERATElevothyroxineMODERATEtramadolMODERATEpantoprazoleMODERATEbupropionMODERATEwarfarin

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.