Escitalopram and Sertraline: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking escitalopram and sertraline together can cause serotonin syndrome, a serious condition with confusion, rapid heartbeat, high fever, and muscle stiffness. You may also bleed more easily if you take these drugs with blood thinners like aspirin or warfarin.

What to do: Tell your doctor about all medicines you take, including blood thinners and pain relievers. Do not stop your medications without talking to your doctor first. Watch for signs of serotonin syndrome or unusual bruising and bleeding, and report them immediately.

Source: FDA-approved drug labeling via openFDA

About These Medications

Escitalopram — View full safety profile, side effects, and all known interactions.

Sertraline — View full safety profile, side effects, and all known interactions.

Other interactions with Escitalopram

MODERATElosartanMODERATEfluoxetineMODERATEvenlafaxineMODERATEoxycodoneMODERATEibuprofenMODERATEmeloxicam

Other interactions with Sertraline

MODERATEvenlafaxineMODERATEwarfarinMODERATEtramadolMODERATElosartanMODERATElevothyroxineMODERATEatenolol

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.