Clopidogrel and Tramadol: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking clopidogrel and tramadol together may reduce how well clopidogrel works to prevent blood clots. This increases your risk of heart attack or stroke.

What to do: Talk to your doctor right away about taking these medicines together. Do not stop either medication on your own. Your doctor may suggest a different pain reliever or adjust your treatment plan.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clopidogrel — View full safety profile, side effects, and all known interactions.

Tramadol — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.