Citalopram and Duloxetine: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking citalopram and duloxetine together can increase serotonin in your body too much, which may cause serious symptoms like confusion, rapid heartbeat, or muscle stiffness. These drugs can also increase bleeding risk, especially if you take blood thinners.

What to do: Tell your doctor you're taking both medications. Don't stop taking either drug without talking to your doctor first. Report any unusual symptoms like confusion, shaking, or unusual bruising. Your doctor may adjust your doses or monitor you more carefully.

Source: FDA-approved drug labeling via openFDA

About These Medications

Citalopram — View full safety profile, side effects, and all known interactions.

Duloxetine — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.