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alprazolam and oxycodone — Drug Interaction

Can you take alprazolam and oxycodonetogether? Here's what FDA data shows.

SEVERE

Interaction Found

Taking alprazolam and oxycodone together is dangerous. Both drugs slow down your brain and breathing. Using them at the same time can cause serious drowsiness, difficulty breathing, and even death.

What to do: Tell your doctor you take both medications. Do not change your doses or stop taking either drug without talking to your doctor first. Your doctor may need to adjust your doses or find different medicines for you. Watch for extreme drowsiness or trouble breathing and call 911 if this happens.

Source: FDA-approved drug labeling via openFDA

About These Medications

alprazolam — View full safety profile, side effects, and all known interactions.

oxycodone — View full safety profile, side effects, and all known interactions.

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SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.