Clopidogrel and Oxycodone: Can You Take Them Together?

Here's what FDA-approved drug labeling shows.

MODERATE

Interaction Found

Taking clopidogrel (a blood thinner) with oxycodone (a pain medicine) may reduce how well clopidogrel works. This could increase your risk of blood clots.

What to do: Tell your doctor if you take both medicines. Do not stop either medication on your own. Your doctor may adjust your doses or switch you to a different blood thinner that works better with oxycodone.

Source: FDA-approved drug labeling via openFDA

About These Medications

Clopidogrel — View full safety profile, side effects, and all known interactions.

Oxycodone — View full safety profile, side effects, and all known interactions.

Other interactions with Clopidogrel

MODERATEdiclofenacMODERATEduloxetineMODERATEescitalopramMODERATEfluoxetineMODERATEibuprofenMODERATEmeloxicam

Other interactions with Oxycodone

SEVEREtramadolSEVEREtrazodoneSEVEREalprazolamMODERATEsertralineMODERATEvenlafaxineMODERATEamoxicillin

Check interactions with other medications:

SafeCheck provides drug interaction information from FDA-approved product labeling (openFDA). This is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions.